https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47175 I² statistic. Meta-analyses employing a fixed effects model were also applied as an additional measure of sensitivity. Results: A total of 27 studies were included which reported on fatherhood after treatment for TC. A meta-analysis of included studies with subgroup analysis was conducted. Subgroup analysis, for the combined studies, indicated an overall pooled pregnancy rate of 22% (95% confidence intervals [CI]: 0.21–0.23; I² = 98.1%) for couples who conceived after TC. Of those couples that became pregnant, 11% (95% CI: 0.07–0.16; I² = 8.5%) experienced a miscarriage. Fatherhood was experienced by 37% (95% CI: 0.35–0.39; I² = 98.1%) of males following treatment for TC. Conclusions: Male cancer patients should be offered discussions, information, and counseling regarding the impact that TC treatment can have on fertility. Furthermore, sperm banking must be recommended to all patients before starting treatment.]]> Wed 14 Dec 2022 15:56:22 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52844 Wed 03 Apr 2024 15:34:58 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46746 Tue 29 Nov 2022 15:18:50 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51870 Thu 21 Sep 2023 10:24:07 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:41465 n = 438). There were 25% (n = 240) of women who became pregnant after autologous HSCT compared with 22% (n = 198) who subsequently became pregnant following allogeneic HSCT. Conclusions: This meta-analysis reflects low pregnancy rates for cancer survivors desiring a family. However, live births are improving over time with new technology and novel therapies. Hence, female cancer patients should be offered timely discussions, counselling and education around fertility preservation options prior to starting treatment with gonadotoxic therapy.]]> Thu 04 Aug 2022 11:26:32 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46604 400 g and/or >20-weeks' gestation, to women diagnosed with breast cancer in the first or second trimesters. Eighteen babies were exposed in utero to chemotherapy. Chemotherapy commenced at a median of 20 weeks gestation, for a mean duration of 10 weeks. Twelve exposed infants were born preterm with 11 by induced labour or pre-labour caesarean section. There were no perinatal deaths or congenital malformations. Our findings show that breast cancer diagnosed during mid-pregnancy is often treated with chemotherapy. Other than induced preterm births, there were no serious adverse perinatal outcomes.]]> Mon 28 Nov 2022 08:30:18 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:50108 Mon 17 Jul 2023 11:54:03 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:55062 Mon 08 Apr 2024 12:39:14 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47905 5 years postdiagnosis. Parents reported on their child's HRQoL (Kidscreen-10), and their own HRQoL (EQ-5D-5L). Parents rated their resilience and fear of cancer recurrence and listed their child's cancer-related late effects. Results: One hundred eighty-two parents of survivors (mean age = 12.4 years old and 9.7 years postdiagnosis) participated. Parent-reported child HRQoL was significantly lower than population norms (48.4 vs. 50.7, p < .009). Parents most commonly reported that their child experienced sadness and loneliness (18.1%). Experiencing more late effects and receiving treatments other than surgery were associated with worse child HRQoL. Parents’ average HRQoL was high (0.90) and no different to population norms. However 38.5% of parents reported HRQoL that was clinically meaningfully different from perfect health, and parents experienced more problems with anxiety/depression (43.4%) than population norms (24.7%, p < .0001). Worse child HRQoL, lower parent resilience, and higher fear of recurrence was associated with worse parent HRQoL. Conclusions: Parents report that young survivors experience small but significant ongoing reductions in HRQoL. While overall mean levels of HRQoL were no different to population norms, a subset of parents reported HRQoL that was clinically meaningfully different from perfect health. Managing young survivors’ late effects and improving parents’ resilience through survivorship may improve HRQoL in long-term survivorship.]]> Mon 06 Feb 2023 15:07:27 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19772 Fri 29 May 2020 17:14:37 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:39719 Fri 17 Jun 2022 17:31:03 AEST ]]>